Dr. Helen Hasapopoulou has been working in the Thalassaemia and Sickle Unit of the AHEPA University Hospital since 1988, performing laboratory and educational work in the blood bank of the hospital. In collaboration with the Department of Internal Medicine she advises on the care of hospitalised patients with haemoglobinopathies or auto- and/or allo-immune haemolysis. Dr. Hasapopoulou has been treating a large cohort of patients with sickle cell disease on small doses of hydroxyurea since 1995. She has further initiated original work on thrombotic complications, on pulmonary hypertension and its treatment with the investigational drug bosentan, on markers of oxidative stress, on predictors of cardiac morbidity and mortality, on pegylated interferon in HCV, on nutrition, on systematic use of laboratory leukoreduction filters, on the use of magnetic resonance imaging of heart and liver for quantitative assessment of iron overload, and others.