Dr. John Old is the director of the National Haemoglobinopathy Reference Laboratory, which carries out molecular diagnosis of thalassaemias for genotyping and prenatal diagnosis for UK patients. He has 30 years of research and diagnostic experience in the thalassaemias and haemoglobinopathies, his main activities being the characterisation of mutations and development of molecular methods for screening and prenatal diagnosis. He has published many chapters on the methods and protocols of thalassaemia diagnosis.